Tucatinib

for

Breast Cancer (HER2+)

Recruiting · Phase 3 · Ages 18+ · 1 visit every 4 - 6 weeks · 5 year duration · Travel subsidy available

States: AL · AZ · AR · CA · CO · LA · DE · DC · FL · GA · HW · IL · IN · KS · KY · MA · MI · MN · MS · MO · MT · NE · NV · NJ · NY · NC · OR · PA · TN · TX · UT · VA · WA

About the trial

Summary
This trial is evaluating whether an FDA-approved cell growth inhibitor outperforms standard therapy for HER-2+ breast cancer that has spread to other parts of the body.
Main Treatment
Tucatinib
Oral
+
T-DM1
Injection
Placebo Treatment
Selinexor
Oral
+
T-DM1
Injection
Eligible Conditions
HER2+ Breast Cancer
Metastatic
or
Inoperable

Phase 1 results Tucatinib + T-DM1 in metastatic breast cancer

About Tucatinib

Comparison of phase 2 results for top prostate cancer drugs

Who is running the study?

Study Director

Study Sponsor

Approximate Timelines

Please note that timelines for treatment and screening will vary by patient.

This trial's locations

AL, AZ, AR, CA, CO, LA, DE, DC, FL, GA, HW, IL, IN, KS, KY, MA, MI, MN, MS, MO, MT, NE, NV, NJ, NY, NC, OR, PA, TN, TX, UT, VA, WA

Alabama
Mobile
Arizona
Chandler · Gilbert · Goodyear · Phoenix · Tucson
Arkansas
Jonesboro
California
Duarte · Encinitas · Fullerton · Orange · Sacramento · San Francisco · Santa Monica · Torrance · Vallejo
Colorado
Aurora · Broomfield · Colorado Springs · Denver · Fort Collins
Delaware
Newark
DC
Washington DC
Florida
Fort Myers · Jacksonville · Miami · Orlando · St. Petersburg · Tampa · West Palm Beach
Georgia
Atlanta · Augusta
Hawaii
Honolulu
Illinois
Arlington Heights · Chicago · Peoria
Indiana
Fort Wayne
Kansas
Kansas City
Louisiana
New Orleans
Maryland
Baltimore · Bethesda · Rockville
Massachusetts
Boston
Michigan
Ann Arbor · Detroit
Minnesota
Minneapolis
Mississippi
Tupelo
Missouri
Kansas City · Saint Louis
Montana
Billings
Nebraska
Omaha
Nevada
Las Vegas
New Jersey
Florham Park · Livingston · New Brunswick
New York
Albany · Stony Brook
North Carolina
Chapel Hill · Charlotte · Durham
Oregon
Portland · Tigurd
Pennsylvania
Philadelphia
Texas
Amarillo · Austin · Bedford · Dallas · Fort Worth · Houston · San Antonia
Utah
Salt Late City
Virginia
Fairfax · Midlothian · Newport News · Salem
Washington
Issaquah · Edmonds · Seattle

Want a second opinion?

Eligibility

Inclusion & Exclusion Checklist

Odds of Eligibility

FAQ

Costs

Do I have to pay to participate in this trial?
There will be no cost for any medical treatment if you choose to participate in this trial.
Will you reimburse me for travel expenses?
Power will reimburse you for up to $500 of travel expenses. There is also likely compensation available to you from the study sponsor, however, this varies by location.
Will my insurance cover participating in the trial?
No insurance filing is required on your part, as there are no costs associated with the medical care you receive via this clinical trial. If you report side effects and need medical care, the costs will be covered for you by the trial sponsor.

Participation

What risks are associated with participating?
Every clinical trial has risks associated with it. Phase 3 trials generally have well-understood risks, as the drugs being studied have already gone through two rounds of research in humans. After you apply to this trial, a physician will walk you through these in detail.
Can I participate if I don’t live in one of the zip codes?
Yes, patients from any zip or state can participate in this trial.
Can I participate if I am not a member of this health network?
Yes, it is possible for anyone to participate in this trial, regardless of  you current health network.

Measurement & Reporting

Up to 5 Years

Progression free survival
Overall survival
Objective response rate
Duration of response

Up to ~9 Months

Adverse event reporting

Want a second opinion?